Original Research

A retrospective study: osteoporosis and hormone replacement therapy

H. June Kuczynski, Mary L. Rogers
Curationis | Vol 12, No 1/2 | a330 | DOI: https://doi.org/10.4102/curationis.v12i1/2.330 | © 1989 H. June Kuczynski, Mary L. Rogers | This work is licensed under CC Attribution 4.0
Submitted: 26 September 1989 | Published: 26 September 1989

About the author(s)

H. June Kuczynski, Professor and Chair Dept, of Maternal-Child Health, Wayne State University, Detroit, Michigan, United States
Mary L. Rogers, Consultant, Brighton, Michigan, United States

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The purpose of this stud y was to determine i f women who undergo hormone replacement therapy postmenopausally, will demonstrate less osteoporosis than women who do not undergo H R T. The osteoporosis subjects were 195 women who volunteered to participate in an NIHsponsored double-blind clinical trial entitled Safely and Efficacy of Fluoride Therapy in Osteoporosis. A convenience sample of 78 controls was obtained by inviting women seeking regular medical attention to join an epidemiological investigation of osteoporosis. The data were analyzed using Chisquare and Student’s t-ratio. The study concludes that future retrospective and prospective analyses appreciate the com plexity of the problem in terms of individual risk for osteoporosis.


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